Delete Prefs.ini:
In this location:
\Documents\My Games\GC3Crusade
Delete the prefs.ini file and try to run the game again (a new one will be created).
Low Prefs:
For clients with low-end video cards (especially Intel PC's with only integrated Video), try running the game with some lower base settings to see if that resolves some of your issues.
Please download the following Prefs.ini file and unzip it in the location following:
http://sd.stardock.com/Support/games/GC3/LowSettings/Prefs.zip
Directory:
C:\Users\YOUR_USERNAME\Documents\My Games\GalCiv3
Gameplay Settings: http://screencast.com/t/0fY8D8OK
Galaxy Settings: http://screencast.com/t/bY1JfuDbK
Try experimenting with these settings pointed out: http://screencast.com/t/pUNAl62jVs
Black Screen while using a Microsoft Surface:
If you're running the game at fullscreen, or a non-native resolution, please change the resolution to the Surface's native resolution or run in windowed mode.
No text visible
Go to this folder (you might need to make hidden files and folders visible in order to see it).
C:\ProgramData\Stardock\Galactic Civilizations III
C:\ProgramData\Stardock\Galactic Civilizations III - Retribution
And delete these files in it
K2FontData_Small.fontdata
K2FontTexture_Small.dds"
Try to run the game again.