Yes, please refer to this document for doing so:
MP Port Change
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Multiplicity Ports
Rule Name Port/.exe
Multiplicity Service 30564
Multiplicity Clipboard 30565
Multiplicity Application (clipboard) Multipl2.EXE
Multiplicity Audio Service 30567
Multiplicity Remote Screen Service 30569 (For Multiplicity 3 only)
Multiplicity Application (Remote screen control
MPRDP64.EXE (For Multiplicity 3 only)
All ports are TCP. The executable names above are for whitelisting the applications within a software-based firewall (Windows Firewall for example).
Windows Firewall
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Allowed Apps
Also in Windows Firewall, all Multiplicity core function need to be in ‘Allowed Apps’
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Changing Multiplicity Ports
These are the keys you will need to add \ edit. PLEASE back up what you have now prior to changing anything. These are examples are for 64-bit machines.
Primary - controlling other machines
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WinKey + R, regedit, enter. Navigate to the following using the name of the Secondary machine you want to connect to; SDROHAN-TEST is the Secondary MP machine in this example
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Note the addition of the string value Port=17. You can choose what ever port you like here (excluding the know commonly used ones of course).
Primary -
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what itself uses
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[HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Stardock\Multiplicity2\Security]
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OverridePortPort2 is the clipboard port. Again, use any port you like here.
Secondary
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[HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Stardock\Multiplicity2\Security]
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OverridePortPort2 is the clipboard port. Again, use any port you like here.
Running a command prompt as admin and netstat -a will show that it is now listening on the new ports
Multiplicity Port Troubleshooting
For any connection issues, the path of least resistance it always a an uninstall \ reboot \ reinstall.
If that fails, please see Multiplicity Connection issues 101